Creatinine Clearance Calculator: method, checked example and practical limits
Estimate adult creatinine clearance with the Cockcroft–Gault equation from age, weight, sex and serum creatinine. The estimated clearance is in mL/min and differs from body-surface-area-normalized eGFR.
Inputs used by this calculator
Creatinine Clearance Calculator uses the fields below. The starting values reproduce the page example; replace them with values from the same units and time period before using the result.
| Input | Starting example | Accepted value | How it is used |
|---|---|---|---|
| Equation sex | Female coefficient | Female coefficient · Male coefficient | Supplies the equation sex quantity used by the published equation or result breakdown. |
| Age (years) | 55 | 18 to 120 | Supplies the age (years) quantity used by the published equation or result breakdown. |
| Weight (kg) | 70 | 20 to 500 | Supplies the weight (kg) quantity used by the published equation or result breakdown. |
| Serum creatinine (mg/dL) | 1 | 0.1 to 30 | Supplies the serum creatinine (mg/dl) quantity used by the published equation or result breakdown. |
Inputs and measurement conventions
The quantities used on this page are Equation sex, Age (years), Weight (kg), Serum creatinine (mg/dL). Start with values for the same situation and read the units attached to each field. The field reference below shows supported choices and numerical limits.
Weight selection matters in unusual body size. Acute renal changes and nonstandard creatinine units can invalidate interpretation.
Method and equation
Use the Cockcroft-Gault age, mass and serum-creatinine relationship with the stated female coefficient where selected.
Creatinine Clearance Calculator uses the following stated relationship: CrCl = (140 − age) × weight ÷ (72 × serum creatinine), multiplied by 0.85 for the female coefficient. Its assumptions determine which question the answer can resolve.
CrCl = (140 − age) × weight ÷ (72 × serum creatinine), multiplied by 0.85 for the female coefficientWorked calculation with the starting values
Equation sex: Female coefficient; Age (years): 55; Weight (kg): 70; Serum creatinine (mg/dL): 1. These starting values give 70.24305556 estimated mL/min creatinine clearance. The calculation breakdown is Age: 55; Weight: 70; Serum creatinine: 1; Equation coefficient: 0.85.
A 55-year-old, 70 kg male with creatinine 1.0 mg/dL estimates 82.64 mL/min.
Reading the answer
The estimated clearance is in mL/min and differs from body-surface-area-normalized eGFR.
Age: 55; Weight: 70; Serum creatinine: 1; Equation coefficient: 0.85. These intermediate quantities make the stated Creatinine Clearance Calculator model inspectable; they should be read together with the main answer rather than treated as independent guarantees.
Common errors and model boundaries
Weight selection matters in unusual body size. Acute renal changes and nonstandard creatinine units can invalidate interpretation.
Drug dosing may require a specified weight method, stable kidney function and clinician interpretation; this is not eGFR.
Independent verification and next decision
Not automatically. Equation, units, body-size normalization and medication-label requirements must be checked by the clinician.
For the Creatinine Clearance Calculator method, compare CrCl = (140 − age) × weight ÷ (72 × serum creatinine), multiplied by 0.85 for the female coefficient with the starting inputs and the calculation table. The linked NIDDK: estimating kidney function and FDA: pharmacokinetics in impaired renal function references identify the relevant definitions, conventions or domain limitations. Retain intermediate precision when comparing a manually worked answer.
Creatinine Clearance Calculator worked-example ledger
| Quantity | Example value | Role |
|---|---|---|
| Equation sex | Female coefficient | Entered assumption |
| Age (years) | 55 | Entered assumption |
| Weight (kg) | 70 | Entered assumption |
| Serum creatinine (mg/dL) | 1 | Entered assumption |
| Main answer | 70.24305556 estimated mL/min creatinine clearance | Calculated from the starting inputs |
| Age | 55 | Intermediate or contextual output |
| Weight | 70 | Intermediate or contextual output |
| Serum creatinine | 1 | Intermediate or contextual output |
| Equation coefficient | 0.85 | Intermediate or contextual output |
Frequently asked questions
Can I substitute eGFR directly for this result?
Not automatically. Equation, units, body-size normalization and medication-label requirements must be checked by the clinician.
Which relationship does the Creatinine Clearance Calculator use?
Use the Cockcroft-Gault age, mass and serum-creatinine relationship with the stated female coefficient where selected. The displayed relationship is CrCl = (140 − age) × weight ÷ (72 × serum creatinine), multiplied by 0.85 for the female coefficient.
What do the starting values produce in the Creatinine Clearance Calculator?
Equation sex: Female coefficient; Age (years): 55; Weight (kg): 70; Serum creatinine (mg/dL): 1. These starting values give 70.24305556 estimated mL/min creatinine clearance. The calculation breakdown is Age: 55; Weight: 70; Serum creatinine: 1; Equation coefficient: 0.85.
How should I interpret this Creatinine Clearance Calculator answer?
The estimated clearance is in mL/min and differs from body-surface-area-normalized eGFR.
Which input mistake most affects the Creatinine Clearance Calculator?
Weight selection matters in unusual body size. Acute renal changes and nonstandard creatinine units can invalidate interpretation.
What is outside this Creatinine Clearance Calculator model?
Drug dosing may require a specified weight method, stable kidney function and clinician interpretation; this is not eGFR.
What to keep in mind
Drug dosing may require a specified weight method, stable kidney function and clinician interpretation; this is not eGFR.
Results are rounded for display in US format, with money in dollars and cents; CSV exports keep full calculation precision. This is a calculation summary, not an official certificate.